The Ren & Stimpy Show (1991)
S5E10 Who's Stupid Now?
Episode Overview
Upon discovering that their show is facing cancellation, Ren declares that they'll do whatever it takes to save it. In response, the producer introduces a new dynamic, flipping their roles: Stimpy becomes the obnoxious skinny character while Ren takes on the role of the bumbling fat fool.
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S5